Using the Universal Math Environment Math-Xpress for teaching and assessment of math courses. In the paper described are the main features of the Universal Math Environment Math-XPress and its use for classroom teaching, home training and assessment of math students at college and university levels. Math-Xpress includes linked modules of equation editor, 2D and 3D graph plotter, CAS expression evaluator and step-to-step solver, dynamic geometry (2D and 3D) and problem solving tutor. Using the XPress-Problem Generator the courses in Calculus, Linear Algebra, Differential Equations, Statistics, Elementary Algebra, Geometry and others have been developed and used at Talpiot teacher’s college and Ariel University in Israel regularly since 2007, involving thousands of students each academic year.