PatchDock and SymmDock: servers for rigid and symmetric docking. Here, we describe two freely available web servers for molecular docking. The PatchDock method performs structure prediction of protein–protein and protein–small molecule complexes. The SymmDock method predicts the structure of a homomultimer with cyclic symmetry given the structure of the monomeric unit. The inputs to the servers are either protein PDB codes or uploaded protein structures. The services are available at The methods behind the servers are very efficient, allowing large-scale docking experiments.

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  1. Pandey, Shrish Kumar; Yadav, Saveg; Goel, Yugal; Temre, Mithlesh Kumar; Singh, Vinay Kumar; Singh, Sukh Mahendra: Molecular docking of anti-inflammatory drug diclofenac with metabolic targets: potential applications in cancer therapeutics (2019)
  2. Lampariello, Francesco; Liuzzi, Giampaolo: Global optimization of protein-peptide docking by a filling function method (2015)
  3. Paragi-Vedanthi, Padmapriya; Doble, Mukesh: Comparison of (PGH_2)binding site in prostaglandin synthases (2010) ioport
  4. Schneidman-Duhovny, Dina; Inbar, Yuval; Nussinov, Ruth; Wolfson, Haim J.: Patchdock and symmdock: Servers for rigid and symmetric docking. (2005) ioport