caGrid: design and implementation of the core architecture of the cancer biomedical informatics grid. MOTIVATION: The complexity of cancer is prompting researchers to find new ways to synthesize information from diverse data sources and to carry out coordinated research efforts that span multiple institutions. There is a need for standard applications, common data models, and software infrastructure to enable more efficient access to and sharing of distributed computational resources in cancer research. To address this need the National Cancer Institute (NCI) has initiated a national-scale effort, called the cancer Biomedical Informatics Grid (caBIGtrade mark), to develop a federation of interoperable research information systems. RESULTS: At the heart of the caBIG approach to federated interoperability effort is a Grid middleware infrastructure, called caGrid. In this paper we describe the caGrid framework and its current implementation, caGrid version 0.5. caGrid is a model-driven and service-oriented architecture that synthesizes and extends a number of technologies to provide a standardized framework for the advertising, discovery, and invocation of data and analytical resources. We expect caGrid to greatly facilitate the launch and ongoing management of coordinated cancer research studies involving multiple institutions, to provide the ability to manage and securely share information and analytic resources, and to spur a new generation of research applications that empower researchers to take a more integrative, trans-domain approach to data mining and analysis. AVAILABILITY: The caGrid version 0.5 release can be downloaded from The operational test bed Grid can be accessed through the client included in the release, or through the caGrid-browser web application

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References in zbMATH (referenced in 10 articles )

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  1. Ruiz, Manuel Garcia; Chaves, Alvin Garcia; Ibañez, Carlos Ruiz; Mazo, Jorge Mario Gutierrez; Giraldo, Juan Carlos Ramirez; Echavarria, Alejandro Pelaez; Diaz, Edison Valencia; Restrepo, Gustavo Pelaez; Munera, Edwin Nelson Montoya; Loaiza, Bernardo Garcia; Al., Et: Mantisgrid: A grid platform for DICOM medical images management in colombia and Latin America (2011) ioport
  2. Boyle, John; Rovira, Hector; Cavnor, Christopher C.; Burdick, David B.; Killcoyne, Sarah A.; Shmulevich, Ilya: Adaptable data management for systems biology investigations (2009) ioport
  3. Clark, Kenneth W.; Gierada, David S.; Marquez, Guillermo; Moore, Stephen M.; Maffitt, David R.; Moulton, Joan D.; Wolfsberger, Mary A.; Koppel, Paul; Phillips, Stanley R.; Prior, Fred W.: Collecting 48, 000 CT exams for the lung screening study of the national lung screening trial (2009) ioport
  4. De La Calle, Guillermo; García-Remesal, Miguel; Chiesa, Stefano; De La Iglesia, Diana; Maojo, Victor: BIRI: a new approach for automatically discovering and indexing available public bioinformatics resources from the literature (2009) ioport
  5. Kunz, Isaac; Lin, Ming-Chin; Frey, Lewis: Metadata mapping and reuse in (caBIG^TM) (2009) ioport
  6. Luo, Yongxing; Jiang, Lijun; Zhuang, Tian-Ge: A grid-based model for integration of distributed medical databases (2009) ioport
  7. Sharma, Ashish; Pan, Tony; Cambazoglu, Berkant Barla; Gurcan, Metin N.; Kurç, Tahsin M.; Saltz, Joel H.: Virtualpacs - A federating gateway to access remote image data resources over the grid (2009) ioport
  8. Kahn, Charles E.: Effective metadata discovery for dynamic filtering of queries to a radiology image search engine. (2008) ioport
  9. Gurcan, Metin N.; Pan, Tony; Sharma, Ashish; Kurç, Tahsin M.; Oster, Scott; Langella, Stephen; Hastings, Shannon; Siddiqui, Khan M.; Siegel, Eliot L.; Saltz, Joel H.: Gridimage: A novel use of grid computing to support interactive human and computer-assisted detection decision support. (2007) ioport
  10. Hastings, Shannon; Oster, Scott; Langella, Stephen; Ervin, David; Kurc, Tahsin; Saltz, Joel: Introduce: An open source toolkit for rapid development of strongly typed grid services (2007) ioport