• iSuc-PseOpt

  • Referenced in 23 articles [sw22429]
  • processes, but it is also associated with some diseases. Therefore, we are challenged...
  • ToppGene Suite

  • Referenced in 8 articles [sw30169]
  • recently reported GWAS-based gene–disease associations (including novel disease genes) representing five diseases. ToppGene...
  • nsSNPAnalyzer

  • Referenced in 5 articles [sw31126]
  • nsSNPAnalyzer: identifying disease-associated nonsynonymous single nucleotide polymorphisms. Nonsynonymous single nucleotide polymorphisms (nsSNPs) are prevalent ... with inherited diseases. To facilitate identifying disease-associated nsSNPs from a large number of neutral ... predict the nsSNP’s phenotypic effect (disease-associated versus neutral). nsSNPAnalyzer, a web-based software...
  • iCar-PseCp

  • Referenced in 18 articles [sw23951]
  • processes but it is also associated with many diseases such as diabetes, chronic lung disease...
  • iRNA-AI

  • Referenced in 26 articles [sw24437]
  • processes, but also closely associated with a series of major diseases. Therefore, knowledge about...
  • Rassoc

  • Referenced in 13 articles [sw25402]
  • important design for testing association between genetic markers and a disease. The Cochran-Armitage trend ... analysis of case-control genetic association studies. The asymptotically optimal CATT can be used when ... inheritance) is known. However, for most complex diseases, the underlying genetic models are unknown. Thus ... other commonly used tests in case-control association studies. For illustration, Rassoc is applied...
  • SNPHarvester

  • Referenced in 6 articles [sw35289]
  • polymorphisms (SNPs) are available for genome-wide association (GWA) studies nowadays. The epistatic interactions ... important in determining individual susceptibility to complex diseases. However, existing methods for SNP interaction discovery ... perform poorly when marginal effects of disease loci are weak or absent. Hence ... groups tend to be statistically associated with diseases, and then harvests those significant SNP groups...
  • dbPTM

  • Referenced in 4 articles [sw29343]
  • curation of literature, but also provide disease association based on non-synonymous single nucleotide polymorphisms...
  • PheWAS

  • Referenced in 2 articles [sw35198]
  • phenome-wide scan to discover gene–disease associations. Results: Four of seven known SNP–disease ... previously unknown statistical associations between these SNPs and diseases at P < 0.01. This study indicates ... feasible method to investigate SNP–disease associations. Further evaluation is needed to determine the validity...
  • LncDisease

  • Referenced in 2 articles [sw34250]
  • based bioinformatics tool for predicting lncRNA-disease associations. LncRNAs represent a large class of noncoding ... roles in a variety of human diseases. There is an urgent need to develop bioinformatics ... method, LncDisease, to predict the lncRNA-disease associations based on the crosstalk between lncRNAs ... VSMCs. In addition, we predicted 6 diseases associated with the lncRNA GAS5 and validated...
  • RBMMMDA

  • Referenced in 2 articles [sw22491]
  • RBMMMDA: predicting multiple types of disease-microRNA associations. Webserver of RBMMMDA: In addition, we built ... prediction of multiple types of miRNA-disease associations based on RBMMMDA method. When visitors choose ... specific disease, potential miRNA associated with this disease based on various association types would...
  • ncPred

  • Referenced in 2 articles [sw17007]
  • ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference. ncPred is an algorithm ... inference of ncRNA-disease association based on recommendation technique. We represent our knowledge through ... network, whose nodes are ncRNAs, targets, or diseases. Interactions ... such a network associate each ncRNA with a disease through its targets. Our algorithm, starting...
  • ReliefF

  • Referenced in 54 articles [sw33465]
  • detecting and characterizing epistasis in genetic association studies. We provide a general overview ... examples of published studies of complex human diseases that have used ReliefF...
  • GCTA

  • Referenced in 22 articles [sw23135]
  • most human complex diseases and traits, SNPs identified by genome-wide association studies (GWAS) explain...
  • TreeDT

  • Referenced in 2 articles [sw37015]
  • mapping method. Given a set of disease-associated haplotypes and a set of control haplotypes ... subtrees with relatively high proportions of disease-associated chromosomes, suggesting shared genetic history for those...
  • DOSE

  • Referenced in 2 articles [sw16933]
  • also implemented to support discovering disease associations of high-throughput biological data. This allows biologists ... biological experiment and identify unexpected disease associations. Comparison among gene clusters is also supported. Availability...
  • Biomine

  • Referenced in 2 articles [sw28409]
  • amounts of data concerning the functions and associations of genes and proteins. Integration of data ... edges, such as protein interactions, gene-disease associations and gene ontology annotations. Edges are weighted ... particular, we formulate protein interaction prediction and disease gene prioritization tasks as instances of link ... task, an established reference set of disease-associated genes is useful, but the results show...
  • DNRLMF-MDA

  • Referenced in 1 article [sw23939]
  • DNRLMF-MDA:Predicting microRNA-disease associations based on similarities of microRNAs and diseases. Discovering miRNA ... disease associations is beneficial to understanding disease mechanisms, developing drugs, and treating complex diseases ... know that discovering the miRNA-disease associations via biological experiments is a time-consuming ... high-efficiency way for predicting miRNA-disease associations. In this study, we propose a method...
  • MDR

  • Referenced in 9 articles [sw22494]
  • which environmental factors are associated with common, complex diseases has become a daunting task. This...
  • iCircDA-MF

  • Referenced in 1 article [sw40050]
  • iCircDA-MF: identification of circRNA-disease associations based on matrix factorization. Circular RNAs (circRNAs ... proposed. Because the circRNA-disease associations with experimental validation are very limited, the potential circRNA ... disease associations are calculated based on the circRNA similarity and disease similarity extracted from ... interaction profiles to predict the circRNA-disease associations. The experimental results on a widely used...