UNPHASED: software for genetic association analysis. UNPHASED is a versatile application for performing genetic association analysis. Some of its more important features are: Analysis of nuclear families and unrelated subjects, and combinations of the two; Analysis of discrete or quantitative traits; Maximum likelihood treatment of missing genotype data and uncertain haplotypes; Global association tests and tests of individual haplotypes; Conditioning tests that allow for previous associations of linked loci; Inclusion of information from additional tag markers; Support for non-genetic covariates; including parent-of-origin; Permutation tests allowing for multiple testing.
Keywords for this software
References in zbMATH (referenced in 6 articles )
Showing results 1 to 6 of 6.
- Zhang, Hong; Mukherjee, Bhramar; Arthur, Victoria; Hu, Gang; Hochner, Hagit; Chen, Jinbo: An efficient and computationally robust statistical method for analyzing case-control mother-offspring pair genetic association studies (2020)
- Bureau, Alexandre; Croteau, Jordie: \textttPolyunphased: an extension to polytomous outcomes of the unphased package for family-based genetic association analysis (2017)
- Bureau, Alexandre; Duchesne, Thierry: On the validity of within-nuclear-family genetic association analysis in samples of extended families (2015)
- Liu, Ying; Lv, Zheng; Wang, Wei: An improved generalized-trend-diffusion-based data imputation for steel industry (2013) ioport
- Hoffmann, Thomas J.; Vansteelandt, Stijn; Lange, Christoph; Silverman, Edwin K.; Demeo, Dawn L.; Laird, Nan M.: Combining disease models to test for gene-environment interaction in nuclear families (2011)
- Laird, Nan M.; Lange, Christoph: The role of family-based designs in genome-wide association studies (2009)