IUPred: web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Summary: Intrinsically unstructured/disordered proteins and domains (IUPs) lack a well-defined three-dimensional structure under native conditions. The IUPred server presents a novel algorithm for predicting such regions from amino acid sequences by estimating their total pairwise interresidue interaction energy, based on the assumption that IUP sequences do not fold due to their inability to form sufficient stabilizing interresidue interactions. Optional to the prediction are built-in parameter sets optimized for predicting short or long disordered regions and structured domains. Availability: The IUPred server is available for academic users at http://iupred.enzim.hu
Keywords for this software
References in zbMATH (referenced in 3 articles )
Showing results 1 to 3 of 3.
- Małysiak-Mrozek, Bożena: Uncertainty, imprecision, and many-valued logics in protein bioinformatics (2019)
- Carugo, Oliviero (ed.); Eisenhaber, Frank (ed.): Data mining techniques for the life sciences (2016)
- Bulashevska, Alla; Eils, Roland: Using Bayesian multinomial classifier to predict whether a given protein sequence is intrinsically disordered (2008)